metformin may help women who struggle with infertility. However, there are other studies indicating that metformin is not effective in improving insulin response in women with pcos. BasicDescription Back to Top. Because metformin can increase your bodys response to insulin, the drug has been used in the treatment of pcos, particularly in women with gestational diabetes. You can talk to your doctor about this risk. You should also talk to your doctor before starting to breastfeed if you are taking metformin. Metformin and pcos Metformin is sometimes used to lower insulin and blood sugar levels in women with polycystic ovary syndrome, or pcos.
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It's sometimes used along with diet, exercise, and other medications to control blood glucose levels. Metformin works by decreasing the amount of sugar you absorb from food and reducing the amount of glucose your liver makes. Your doctor will advise you on when to stop and restart the drug. Women with pcos may have enlarged ovaries containing fluid, or follicles. Or click here to find more resources for healthier living! The drug can cause a loss of appetite and feelings of fullness that lead to this effect. See our current special offers on certain Merck medicines for eligible patients, including savings coupons and free trial offers. Oral contraceptives are the first-choice therapy in most non-diabetic patients in pcos. Some laboratory animals that were given high doses of metformin developed non-cancerous abnormal growths of tissue (polyps) on the uterus. Pcos causes irregular or no menstrual periods, irregular ovulation, and high levels of androgens (male hormones ) in the body, sometimes leading to hirsutism (excessive growth of facial or body hair on women) Lowering blood sugar and insulin may help regulate menstrual cycles, start ovulation. Researchers believe excess insulin may affect the ovaries by increasing androgen production, which may interfere with the ovaries' ability to ovulate.
If you have insulin resistance, your body cannot use insulin effectively. Oral contraceptives are preferred over metformin for endometrial protection, hyperandrogenic symptoms, and restoration of normal menstrual cycles. Don't stop taking the drug without talking to your physician.